Anti-UAV Defense System is composed of front-end equipments such as detection radar, RF detector, E/O tracking camera, RF jamming or spoofing device and UAV control platform software. When the droneenters the defense zone, the detection unit outputs accurate position information through active distance, angle, speed and height. On entering the warning zone, the system will determine independently and start the jamming device to interfere the drone communication, so as to make the drone returning or landing. The system supports multi devices and multi zones management and can realize 7*24 all-weather monitoring and protection against drone invasion.